Clean up Pythran setup in cythonize() and make it a little more robust by also looking at the extension, in case it already has the "np_pythran" option set.

Implement a "--pgo" option for the Jupyter magic that applies profile guided optimisation during C compilation.

Update README on pyximport

Closes #1859.

Closes #1860.

Release buffer on validation errors. My guess is that we previously just leaked the buffer owner in that case.

Closes #1858.

Check result of "declare_builtin()" because it might a) not have been found and b) not actually be a builtin. In both cases, it's actually not a literal.

Add missing special signature for "__getattribute__" method in order to enforce it and mark the method as special.

Replace closure class special casing from slot generation code and replace it with saner and more general "is_special" check.